Karl Deisseroth (Stanford / HHMI): Development of Optogenetics

Dr. Karl Deisseroth gives a retrospective on the development of optogenetics, a technology that has revolutionized neuroscience. Optogenetics uses pulses of light to alter an animal’s behavior by taking advantage of light-sensitive ion conductance regulators called microbial opsins, which convert a photon of light into an electrical signal. By using genetics to express opsins in particular neurons, scientists can control the activation or suppression of neurons with pulses of light and measure the resulting behavioral changes in an animal., January 01, 2016